The valley's west-facing orientation makes Ramosch one of the warmest and sunniest places in the Engadin. The Kuppe Mottata above Ramosch has been inhabited since the Middle Bronze Age. Ramosch later became the traffic hub of the Engadin. The transalpine traffic axis between Munich and Milan here crossed the Inntalweg (Inn Valley route), giving Ramosch strategic importance along this vital trading route.

It is thus no coincidence that this is the site of the Engadin's oldest Christian church dating from the 6th century and that a fortified castle complex was also built here at the turn of the century. Both buildings can still be visited today.

Castle Ramosch, commonly known as Tschanüff since the 16th century, is an impressive building with an outer bailey, main castle and a keep dating from the 13th century. The castle has been uninhabited since the 18th century and now lies in ruins. Not far from Tschanüff is the disused Swiss Army fortification from the period between the two World Wars. It is visible to the naked eye but not open to visitors.

Ramosch Church is dedicated to St. Florian, who worked as a priest in Ramosch in the 7th century and is reputed to have turned water from the village fountain into wine. Ramosch has been a significant place of pilgrimage to the grave of St. Florian since the 9th century.

The history of Ramosch is particularly chequered. For centuries the village was ruled by various masters until in 1652, Ramosch and the entire valley was finally ransomed from the Austrians. During this time, Ramosch was also known as the granary of the Engadin. The south-facing slopes made it particularly suitable for cultivating corn. The slopes were terraced in impressive fashion and the steps are still visible today. From the 20th century however, agriculture gradually became less important.